Question:medium

A patient shows frequent fatigue and weakness. Blood examination reveals that some red blood cells are sickle-shaped. Based on these observations, answer the following:
(a) Identify the reason for this disease.
(b) In what other ways does this genetic defect affect the body?

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Remember: Sickle cell anaemia is caused by a mutation in haemoglobin gene, leading to abnormal RBC shape and reduced oxygen-carrying capacity.
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