Step 1: Build a nucleotide from scratch. Start with a pentose sugar and attach a nitrogenous base at C1 to make a nucleoside.
Step 2: Esterify the sugar at the 5-prime carbon with phosphate; the resulting base + sugar + phosphate unit is the nucleotide.
Step 3: Nowhere in this assembly does a fatty acid appear; fatty acids belong to triglycerides and phospholipids. Among the options, only fatty acid is foreign to nucleotide structure.
\[\boxed{\text{Fatty acid}}\]