Select correct statements regarding mutation.
A. A point mutation involves substitution of a single nucleotide pair.
B. Frameshift mutations result from insertion or deletion of nucleotides not in multiples of 3.
C. Silent mutations always alter the amino acid sequence of a protein.
D. Mutagens can be physical, chemical or biological agents.
E. Auxotrophs can be easily grown on minimal media.
Choose the correct answer from the options given below :