Malaria symptoms in humans manifest as: Recurrent high fever accompanied by chills. Profuse sweating and shivering. Headaches and generalized body pain. Nausea and vomiting. Profound fatigue and weakness.These symptoms arise from the release of merozoites into the bloodstream following the rupture of red blood cells.- The *Plasmodium* parasite invades red blood cells, proliferates internally, and ultimately causes their lysis. This destruction liberates toxic compounds like haemozoin, which stimulates the immune system, inducing fever and chills.