Question

Which type of "blinding" is most commonly utilized in Randomized Controlled Trials (RCTs) to reduce bias?

• A. Single-blind
• B. Double-blind
• C. Triple-blind
• D. Open-label

Hint:

Double-blind = \textbf{Participant + Investigator unaware} $\Rightarrow$ Best balance of practicality and bias control.

Answer 1

The Correct Option is B

Step 1: Understanding the Concept:
Blinding is a method used to prevent participants and researchers from knowing which treatment is being given, thereby reducing psychological and observer bias.
Step 2: Detailed Explanation:
- Single-blind: Only the patient doesn't know.
- Double-blind: Both the patient and the doctor/investigator don't know who is getting the treatment vs. the placebo. This is the standard in clinical trials to ensure objective results.
- Triple-blind: The patient, the doctor, and the person analyzing the data are all unaware.
- Open-label: Everyone knows the treatment allocation.
Step 3: Final Answer:
Double-blind is the most common form of blinding used in RCTs.