Question:medium
Which statement is not true regarding Crohn's disease?
Which statement is not true regarding Crohn's disease?
Show Hint
Crohn's skips; continuous mucosal disease belongs to ulcerative colitis - pick the odd one out.
Updated On: Jun 23, 2026
- Rectum is not involved
- Continuous lesion visualized in endoscopy
- Non-caseating granulomas
- Cobblestone appearance
Show Solution
The Correct Option is B
Solution and Explanation
Step 1: The question wants the one statement that does NOT fit Crohn's disease, so build a quick true/false table from the Crohn's versus ulcerative colitis comparison.
Step 2: Key discriminator: Crohn's is patchy with $skip$ $lesions$, while ulcerative colitis is a continuous, confluent process spreading proximally from the rectum. Hence describing a continuous endoscopic lesion is a colitis feature, not Crohn's - that statement is false.
Step 3: Verify the rest are genuine Crohn's traits. Rectal sparing is typical, non-caseating granulomas are the classic histology, and cobblestoning arises from criss-crossing linear ulcers separated by oedematous mucosa. All true.
Step 4: Only the continuous-lesion claim breaks the pattern, so it is the untrue statement and the correct choice.
\[\boxed{\text{Continuous lesion visualized in endoscopy}}\]
Step 2: Key discriminator: Crohn's is patchy with $skip$ $lesions$, while ulcerative colitis is a continuous, confluent process spreading proximally from the rectum. Hence describing a continuous endoscopic lesion is a colitis feature, not Crohn's - that statement is false.
Step 3: Verify the rest are genuine Crohn's traits. Rectal sparing is typical, non-caseating granulomas are the classic histology, and cobblestoning arises from criss-crossing linear ulcers separated by oedematous mucosa. All true.
Step 4: Only the continuous-lesion claim breaks the pattern, so it is the untrue statement and the correct choice.
\[\boxed{\text{Continuous lesion visualized in endoscopy}}\]
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