Break down complex multi-grid patterns by analyzing each quadrant independently as its own separate number sequence. Solving one quadrant (like the Top-Left: 2, 3, 4, 5) often reduces the options to one or two choices.
Step 1: Find the rule. Track how dot counts in each quadrant change across the 2x2 grids in the series. Step 2: Apply it. Extend the progression to the missing grid. \[ \boxed{\text{Option 3 (Fig C)}} \]