Delhi's Yamuna River faces its most substantial pollution from domestic waste discharge. Accelerated urbanization results in the direct release of untreated sewage, household refuse, and industrial wastewater into the river, causing severe contamination with high toxin and waste concentrations. Although agricultural pesticide and fertilizer use contributes to pollution in farming regions, domestic waste dumping remains the principal cause of Yamuna's pollution in Delhi.Therefore, the correct choice is (B) Dumping of domestic waste.