Question

Which one of the following is an autosomal recessive disorder?

• A. Albinism
• B. Huntington's syndrome
• C. Marfan's syndrome
• D. Neurofibromatosis-1

Hint:

Three options are dominant; the pigment disorder is the recessive one.

Answer 1

The Correct Option is A

Step 1: Sort each option by its inheritance pattern, then keep the recessive one.
Step 2: Huntington's disease, Marfan syndrome and NF-1 are well-known autosomal dominant conditions, each needing only one mutant allele.
Step 3: Albinism, by contrast, needs two defective alleles in a pigment-pathway gene such as tyrosinase, the hallmark of autosomal recessive transmission.
Step 4: So three options are dominant and only albinism is recessive.
\[\boxed{\text{Albinism}}\]