Question

Which of the following statements is NOT correct for vecuronium?

• A. It has a high incidence of cardiovascular side effects
• B. It has short duration of neuromuscular block
• C. In usual doses, dose adjustment is not required in kidney disease
• D. It has high lipophilic property

Hint:

Vecuronium is known for cardiovascular stability, so calling it high risk for heart side effects is the wrong statement.

Answer 1

The Correct Option is A

Vecuronium is a common non depolarising muscle relaxant, and this question wants the one statement about it that is false.

1. High incidence of cardiovascular side effects: vecuronium is prized precisely because it barely touches heart rate or blood pressure at normal doses, unlike pancuronium. Calling it high risk for cardiovascular side effects goes against its known profile, so this statement is false.
2. Short duration of neuromuscular block: compared with long acting relaxants, vecuronium wears off in a comparatively short time, which matches how it is actually used, so this statement holds up.
3. No dose adjustment needed in kidney disease at usual doses: since vecuronium leaves the body mainly through the liver and bile rather than the kidney, a single normal dose in a patient with kidney disease does not need special adjustment, making this statement correct.
4. High lipophilic property: as an aminosteroid compound, vecuronium is fat soluble, and this is exactly what allows liver uptake and biliary clearance, so this statement is also correct.

Only the claim about frequent cardiovascular side effects goes against what vecuronium is actually known for, so that is the incorrect statement.

Let's summarize:

• Vecuronium is valued for its cardiovascular stability, not for causing heart side effects.
• Its short duration, safe use in usual renal impairment doses, and lipophilic nature are all accurate.

The incorrect statement is that vecuronium has a high incidence of cardiovascular side effects.