Question:medium

Which of the following statements are correct about poly-A-tail addition to a pre-mRNA: A. Polyadenylation signals in mammalian cells consist of the hexanucleotide AAUAAA in addition to upstream and downstream (U- or GU-rich) elements.
B. Polyadenylation signals consist of the hexanucleotide GGUAAA.
C. Poly-A polymerase adds a poly-A tail consisting of about 50 Adenines to the 3' end.
D. Poly-A polymerase adds a poly-A tail consisting of about 200 Adenines to the 3' end.

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AAUAAA is the signal. Think of “A lot” of A's---roughly 200 of them.
Updated On: May 28, 2026
  • B and C Only
  • A and C Only
  • D Only
  • A and D Only
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The Correct Option is D

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