Step 1: Use the interior/boundary/exterior test for feature relationships.
A convenient way to classify how a line $L$ relates to a polygon $A$ is to check where the points of $L$ fall relative to the three parts of $A$: its interior $A^{\circ}$, its boundary $\partial A$, and its exterior $A^{-}$ (everything outside $A$). Every standard topological line-area relation can be described purely in terms of these three intersections.
Step 2: Test "contained in".
If every point of $L$ lies in $A^{\circ} \cup \partial A$ and no point of $L$ lies in $A^{-}$, then $L$ is said to be contained in (within) $A$. This condition is checkable using only interior/exterior membership, with no distance or angle measurement needed, so it is a genuine topological relation, and it correctly describes a line-area relationship.
Step 3: Test "crosses".
If $L$ has points in both $A^{\circ}$ and $A^{-}$, meaning the line has a nonzero-length part inside the polygon and a nonzero-length part outside it, and it also meets $\partial A$ where it passes through the boundary, then $L$ is said to cross $A$. This too is defined purely by interior/exterior/boundary membership, so it is a genuine topological line-area relation.
Step 4: Test "parallel to".
Parallelism between $L$ and some edge or overall orientation of $A$ is defined by comparing the direction vector of $L$ to a direction vector associated with $A$, for example $\vec{L} \parallel \vec{e}$ for edge $e$ of $A$. This test uses angle/direction, not interior-exterior-boundary membership, so it does not fit the topological relation framework at all and is instead a directional/metric property.
Step 5: Test "nearest to".
Nearness between $L$ and $A$ is defined by minimizing the Euclidean distance $\min_{p \in L, q \in A} \, \text{dist}(p, q)$, this is explicitly a distance based, metric quantity, and again cannot be expressed purely through interior/exterior/boundary set membership, so it also falls outside the topological relation framework.
Step 6: Conclusion.
Only the interior/exterior/boundary based relations, "line is contained in area" and "line crosses area", qualify as valid line-area spatial (topological) relationships among the four options given.
\[ \boxed{\text{Line is contained in area, and Line crosses area}} \]