Question:medium

Which of the following is used to stain endospores?

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Associate stains with specific procedures: Crystal Violet and Safranin are key to Gram staining. Malachite Green and Safranin are key to endospore staining. This helps in quick recall during exams.
Updated On: Feb 18, 2026
  • Safranin
  • Malachite green
  • Crystal violet
  • Brilliant green
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The Correct Option is B

Solution and Explanation

Step 1: Concept Overview:
The question focuses on identifying the primary stain utilized in endospore staining. Endospores are dormant, resilient, non-reproductive structures produced by certain bacteria. Their resistant outer layer makes them difficult to stain using typical methods.
Step 2: Detailed Explanation:
The Schaeffer-Fulton method is the most common endospore staining technique. This differential staining method includes these steps and reagents:


Primary Stain: Malachite green is applied to the bacterial sample. Heat acts as a mordant, facilitating the stain's penetration into the resistant endospores. At this point, both vegetative cells and endospores appear green.

Decolorization: Water is used to rinse the sample. The water-soluble malachite green is easily washed away from the vegetative cells, but not from the endospores.

Counterstain: Safranin is applied, staining the now-colorless vegetative cells pink or red. The endospores retain the green color from the primary stain.

Considering the other options:


Safranin: Functions as the counterstain in both Gram staining and endospore staining.

Crystal violet: Serves as the primary stain in Gram staining.

Brilliant green: A stain often employed as a selective agent in culture media.

Step 3: Final Answer:
According to the standard Schaeffer-Fulton endospore staining procedure, malachite green is the primary stain used to specifically color the endospores.
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