Question:hard
Which of the following is the least common corneal dystrophy?
Which of the following is the least common corneal dystrophy?
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Rank granular, lattice, and macular by frequency; the rarest deposits mucopolysaccharide.
Updated On: Jun 24, 2026
- Macular dystrophy
- Lattice type I
- Lattice type III
- Granular corneal dystrophy
Show Solution
The Correct Option is A
Solution and Explanation
This question lines up the main stromal corneal dystrophies and asks which is seen least often. A simple way to rank them is by frequency and by what they deposit. Granular dystrophy tops the list as the most common; it lays down crumb-like hyaline material in the stroma that lights up with Masson trichrome. Lattice dystrophy comes next; here the deposits are amyloid, arranged as fine branching lines that stain with Congo red, and type I is a familiar inherited pattern. Macular dystrophy sits at the bottom for frequency. It is inherited in an autosomal recessive manner, deposits abnormal mucopolysaccharides (glycosaminoglycans) that take up Alcian blue and colloidal iron, and clouds the cornea diffusely all the way to the edge, making it the most severe yet the rarest of the trio. Putting the choices in order, granular is commonest, lattice is in the middle, and macular dystrophy is the rare one. So the least common corneal dystrophy among the options is macular dystrophy. \[\boxed{\text{Macular dystrophy}}\]
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