Understanding the Question:
The question asks which listed set of tests is done as in-process quality control during tablet manufacturing.
Key Concept:
In-process tests are pulled from the tablet press at set intervals while compression is still running, to catch a drifting machine before a whole batch is out of specification, unlike finished-product release tests that run once compression is complete.
Checking Each Option:
Zeta-sizing belongs to liquid or nanoparticle formulations, not to compressed tablets.
Dissolution testing is a finished-product release test that takes real time to run and needs a complete tablet to test.
Drug content uniformity and puncture testing are mainly applied as finished-product or film-strength checks rather than routine in-line sampling.
Hardness, friability and average weight are pulled straight from the running press at timed intervals to confirm the batch stays within spec while it is still being made.
Final Answer:
Hardness, Friability and Average weight are the in-process QC tests for tablets.