Question:easy
Which of the following is an orally active direct factor Xa inhibitor?
Which of the following is an orally active direct factor Xa inhibitor?
Show Hint
Look for the oral "-xaban" drug, not the "-gatran" thrombin blocker.
Updated On: Jun 23, 2026
- Rivaroxaban
- Argatroban
- Dabigatran
- Bivalirudin
Show Solution
The Correct Option is A
Solution and Explanation
Step 1: Sort the four drugs by the clotting-factor target they hit. Direct oral anticoagulants split into two groups: those targeting thrombin (IIa) and those targeting Xa.
Step 2: The "-xaban" suffix flags the factor Xa inhibitors. Rivaroxaban fits this pattern and is taken by mouth, satisfying both criteria in the stem.
Step 3: Dabigatran ends in "-gatran" and is the oral direct thrombin inhibitor, so it is excluded. Argatroban and bivalirudin are injectable thrombin inhibitors used during procedures such as in heparin-induced thrombocytopenia, so neither is oral nor a Xa blocker.
Step 4: Matching "oral" plus "direct Xa" leaves a single correct choice.
\[\boxed{\text{Rivaroxaban}}\]
Step 2: The "-xaban" suffix flags the factor Xa inhibitors. Rivaroxaban fits this pattern and is taken by mouth, satisfying both criteria in the stem.
Step 3: Dabigatran ends in "-gatran" and is the oral direct thrombin inhibitor, so it is excluded. Argatroban and bivalirudin are injectable thrombin inhibitors used during procedures such as in heparin-induced thrombocytopenia, so neither is oral nor a Xa blocker.
Step 4: Matching "oral" plus "direct Xa" leaves a single correct choice.
\[\boxed{\text{Rivaroxaban}}\]
Was this answer helpful?
0
