Question:medium

Which of the following is a characteristic symptom of Down syndrome?

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Down syndrome is caused by trisomy of chromosome 21 and is often associated with congenital heart defects, intellectual disabilities, and distinct facial features.
Updated On: Jan 13, 2026
  • Abnormal growth of hair.
  • Heart murmurs.
  • Skin rash.
  • Eye color changes.
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The Correct Option is B

Solution and Explanation

Step 1: Down syndrome overview. Down syndrome is a genetic condition resulting from an extra copy of chromosome 21 (trisomy 21), leading to diverse physical, developmental, and physiological differences.

Step 2: Typical manifestations. Common signs include cardiac anomalies like heart murmurs, a flattened facial structure with upward-slanting eyes, and varying degrees of intellectual disability and developmental delays.

Step 3: Evaluation of choices.Option (A): Incorrect. Aberrant hair growth is not a defining symptom.

Option (B): Correct. Heart murmurs frequently accompany congenital heart conditions in individuals with Down syndrome.

Option (C): Incorrect. Skin eruptions are not characteristic.

Option (D): Incorrect. Variations in eye color are not linked to Down syndrome. \[ \therefore \text{The correct answer is: Heart murmurs.} \]

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