Step 1: List the four pairs and the midline gaps with their approximate closure times, since the question is purely about timing. Posterior closes first, around 2-3 months.
Step 2: Working through the timeline: the sphenoidal (anterolateral) follows near 6 months, then the mastoid (posterolateral) from 6 to 18 months.
Step 3: The anterior fontanelle, the largest and most clinically useful for assessing hydration and intracranial pressure, persists the longest and closes around 18 to 24 months of age.
Step 4: Therefore, among the choices given, the anterior fontanelle is the final one to ossify; the anterolateral and lateral (mastoid) ones close well before it.
\[\boxed{\text{Anterior}}\]