Question:medium
Which of the following exocrine glandular ducts are not obstructed in cystic fibrosis:
Which of the following exocrine glandular ducts are not obstructed in cystic fibrosis:
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Serous sweat glands give salty sweat but the duct stays open.
Updated On: Jun 23, 2026
- Pancreas
- Lung
- Sweat gland
- All of above
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The Correct Option is C
Solution and Explanation
Step 1: Split CF glands into two groups - mucous and serous. The CFTR defect makes mucous secretions thick and sticky, so the ducts of mucus glands clog. Step 2: Mucous-type involvement explains bronchiectasis in the lungs, pancreatitis with malabsorption from a blocked pancreatic duct, and obstructive jaundice from plugged bile ductules. Step 3: The sweat gland is a serous gland. Here the problem is not a mucus plug but failure to reabsorb chloride and sodium, so the sweat is salty while the duct itself remains open and unobstructed. Step 4: Because the duct stays patent, sweat can be collected for the pilocarpine iontophoresis sweat chloride test. So among the choices, only the sweat gland duct escapes obstruction. \[\boxed{\text{Sweat gland}}\]
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Top Questions on Cystic fibrosis
- Consider the following statements: Cystic fibrosis of the pancreas
1. Is an autosomal dominant disorder.
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