Question:medium

Which of the following events are critical in development of irreversible cell injury:
A. Loss of membrane integrity
B. Loss of mitochondrial function
C. Lipid accumulation
D. Calcium influx
Choose the correct answer from the options given below:

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To remember this concept, think of the "membrane-calcium-mitochondria" triad. Together, they define irreversible injury. Fatty change (lipid accumulation) and cellular swelling are classic reversible changes.
Updated On: Aug 13, 2026
  • A, B and D only
  • A, B and C only
  • B, C, and D only
  • A and C only
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The Correct Option is A

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