Question:medium

Which of the following enzymes of Glycolytic pathway has achieved the catalytic perfection in the sense that any increase in its catalytic efficiency would not increase the rate of reaction catalysed by it?

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A "catalytically perfect" enzyme has its reaction rate limited solely by substrate diffusion, which typically lies in the range of \(10^8 - 10^9 \text{ M}^{-1}\text{s}^{-1}\).
TPI is the classic biochemistry textbook example of this phenomenon.
  • Hexokinase
  • Pyruvate kinase
  • Triose phosphate isomerase
  • Phosphofructokinase
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The Correct Option is C

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