Question

Which of the following complexes is used to be as an anticancer agent?

• A. cis-[PtCl₂(NH₃)₂]
• B. cis-K₂[PtCl₂Br₂]
• C. Na₂CoCl₄
• D.

Answer 1

The Correct Option is A

The complex that is used as an anticancer agent among the given options is \text{cis-[PtCl}_2\text{(NH}_3\text{)}_2\text{]}. This complex is commonly known as cisplatin.

1. The anticancer properties of \text{cis-[PtCl}_2\text{(NH}_3\text{)}_2\text{]} are well-known in medicinal chemistry. Cisplatin is one of the most widely used chemotherapeutic drugs.
2. Cisplatin works primarily by interacting with DNA in cancer cells. It forms cross-links with the DNA, obstructing DNA replication and transcription, thereby preventing the cancer cells from proliferating.
3. On examining other options:
   • \text{cis-K}_2\text{[PtCl}_2\text{Br}_2\text{]} does not have recognized anticancer properties.
   • \text{Na}_2\text{CoCl}_4 is not related to cancer treatment either and does not contain platinum, which is typically the metal in complexes used for anticancer purposes.

Therefore, the correct answer is \text{cis-[PtCl}_2\text{(NH}_3\text{)}_2\text{]} due to its established role as an anticancer agent.