Question:medium
Which is the antibiotic of choice for a bedridden patient with catheter-related UTI and pneumonia?
Which is the antibiotic of choice for a bedridden patient with catheter-related UTI and pneumonia?
Show Hint
Resistant organisms make beta-lactamase, so you need an inhibitor combination.
Updated On: Jun 24, 2026
- Amoxicillin
- Beta lactam antibiotic with a beta lactamase inhibitor
- 3rd generation cephalosporins
- 2nd generation cephalosporins
Show Solution
The Correct Option is B
Solution and Explanation
Step 1: In a debilitated, catheterized inpatient with both a urinary and a respiratory infection, the likely pathogens frequently produce beta-lactamase enzymes that destroy simple penicillins.
Step 2: The rational pick is a beta lactam paired with a beta lactamase inhibitor; the inhibitor shields the antibiotic, restoring its broad activity against these organisms.
Step 3: This combination therefore gives potent, dependable coverage for the UTI and pneumonia together.
Step 4: Unprotected amoxicillin would be inactivated, and the second- or third-generation cephalosporin choices are less optimal for this resistance-prone setting.
\[\boxed{\text{Beta lactam with a beta lactamase inhibitor}}\]
Step 2: The rational pick is a beta lactam paired with a beta lactamase inhibitor; the inhibitor shields the antibiotic, restoring its broad activity against these organisms.
Step 3: This combination therefore gives potent, dependable coverage for the UTI and pneumonia together.
Step 4: Unprotected amoxicillin would be inactivated, and the second- or third-generation cephalosporin choices are less optimal for this resistance-prone setting.
\[\boxed{\text{Beta lactam with a beta lactamase inhibitor}}\]
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