Question

Which functional groups of glucose interact to form cyclic hemiacetal leading to pyranose structure?

• A. Aldehyde group and hydroxyl group at C – 4
• B. Aldehyde group and hydroxyl group at C – 5
• C. Ketone group and hydroxyl group at C – 4
• D. Ketone group and hydroxyl group at C – 5

Hint:

Monosaccharides like glucose can cyclize to form hemiacetals, where the aldehyde group reacts with a hydroxyl group on the same molecule.

Answer 1

The Correct Option is B

A six-membered ring cyclic hemiacetal is formed when the aldehyde group at C – 1 of glucose in its pyranose form interacts with the hydroxyl group at C – 5. This is a characteristic reaction for monosaccharides leading to cyclic structures.