Question:easy
What is the recommended dose of equine rabies immunoglobulin for post-exposure prophylaxis?
What is the recommended dose of equine rabies immunoglobulin for post-exposure prophylaxis?
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Equine RIG is 20 IU/kg; F(ab)2 products are 40 IU/kg.
Updated On: Jun 24, 2026
- 10 IU/kg
- 20 IU/kg
- 30 IU/kg
- 40 IU/kg
Show Solution
The Correct Option is B
Solution and Explanation
Step 1: For a severe (category III) animal bite, ready-made antibody in the form of rabies immunoglobulin is placed in and around the bite wound to neutralise virus before the vaccine takes effect.
Step 2: The standard equine (horse-derived) immunoglobulin preparation is administered at $20$ IU per kilogram of body weight.
Step 3: The higher figure of $40$ IU/kg applies only to F(ab)2 fragment preparations, so option d is a trap; 10 and 30 IU/kg are not recognised dosing schedules.
Step 4: Hence the dose asked for is 20 IU/kg.
\[\boxed{20\ \text{IU/kg}}\]
Step 2: The standard equine (horse-derived) immunoglobulin preparation is administered at $20$ IU per kilogram of body weight.
Step 3: The higher figure of $40$ IU/kg applies only to F(ab)2 fragment preparations, so option d is a trap; 10 and 30 IU/kg are not recognised dosing schedules.
Step 4: Hence the dose asked for is 20 IU/kg.
\[\boxed{20\ \text{IU/kg}}\]
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