Question:easy
What is the choice of treatment for idiopathic thrombocytopenic purpura (ITP)?
What is the choice of treatment for idiopathic thrombocytopenic purpura (ITP)?
Show Hint
The organ that both destroys platelets and makes the antibody.
Updated On: Jun 23, 2026
- Blood transfusion
- Spontaneous recovery
- IV infusion
- Splenectomy
Show Solution
The Correct Option is D
Solution and Explanation
Step 1: ITP is an antibody mediated platelet destruction disorder, and the spleen plays a double role: it clears the antibody tagged platelets and it manufactures much of the offending autoantibody. Step 2: Acute management leans on steroids and intravenous immunoglobulin, yet these do not cure the chronic disease. Step 3: When the disease is chronic or fails medical therapy, the operation that addresses both pathogenic roles at once is splenectomy, producing durable remission in the majority. Step 4: Transfusing platelets is futile because they are quickly destroyed, spontaneous recovery is unreliable in chronic disease, and a vague IV infusion is not a defined cure. So the chosen treatment is removal of the spleen. \[\boxed{\text{Splenectomy}}\]
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