Insulin resistance is characterized by reduced cellular sensitivity to insulin. Insulin, a hormone, normally facilitates glucose uptake by cells to manage blood sugar. When cells become resistant, the pancreas increases insulin production to compensate. This can ultimately result in hyperglycemia and type 2 diabetes. Key associated factors include:
- Obesity, particularly abdominal adiposity.
- Sedentary lifestyle.
- Unhealthy dietary patterns rich in refined carbohydrates and lipids.
- Hereditary factors.
Management strategies involve adopting healthy lifestyle modifications such as consistent physical activity, a balanced diet, and achieving a healthy body weight.