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What is meant by Insulin resistance?

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Preventing insulin resistance is key to reducing the risk of type 2 diabetes and cardiovascular diseases.
Updated On: Jan 14, 2026
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Solution and Explanation

Insulin resistance is characterized by reduced cellular sensitivity to insulin. Insulin, a hormone, normally facilitates glucose uptake by cells to manage blood sugar. When cells become resistant, the pancreas increases insulin production to compensate. This can ultimately result in hyperglycemia and type 2 diabetes. Key associated factors include:
  • Obesity, particularly abdominal adiposity.
  • Sedentary lifestyle.
  • Unhealthy dietary patterns rich in refined carbohydrates and lipids.
  • Hereditary factors.
Management strategies involve adopting healthy lifestyle modifications such as consistent physical activity, a balanced diet, and achieving a healthy body weight.
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