Question:medium
Type E adverse reaction is?
Type E adverse reaction is?
Show Hint
E for End of use - reaction on stopping the drug.
Updated On: Jun 24, 2026
- Toxicity
- Augmented effect
- Teratogenesis
- Withdrawal reaction
Show Solution
The Correct Option is D
Solution and Explanation
Step 1: Use the alphabet mnemonic for adverse reactions - A Augmented, B Bizarre, C Chronic, D Delayed, E End of use. Type E therefore equals withdrawal phenomena.
Step 2: The prototype is clonidine, whose sudden discontinuation triggers a sympathetic rebound and hypertensive surge, the textbook Type E event.
Step 3: Sort the distractors - augmented (predictable, dose-linked) is Type A, teratogenesis sits in the Delayed Type D group, and general toxicity is again a Type A excess effect, leaving withdrawal as the only Type E answer.
\[\boxed{\text{Withdrawal reaction}}\]
Step 2: The prototype is clonidine, whose sudden discontinuation triggers a sympathetic rebound and hypertensive surge, the textbook Type E event.
Step 3: Sort the distractors - augmented (predictable, dose-linked) is Type A, teratogenesis sits in the Delayed Type D group, and general toxicity is again a Type A excess effect, leaving withdrawal as the only Type E answer.
\[\boxed{\text{Withdrawal reaction}}\]
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