Question:medium

Treatment of an erythematous skin rash with multiple pus lakes in a pregnant woman is:

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Pustular psoriasis of pregnancy needs a drug safe for the fetus.
Updated On: Jun 24, 2026
  • Corticosteroids
  • Retinoids
  • Methotrexate
  • Psoralen with PUVA
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The Correct Option is A

Solution and Explanation

Translate the description first. A pregnant woman with red skin carrying many small pus collections is the classic look of impetigo herpetiformis, the pustular psoriasis seen in pregnancy. The pustules are sterile, hence pus lakes, not true infection.

The key driver of the answer is pregnancy safety. The disease needs prompt control because it can bring fever, low calcium, and danger to the baby. So we must pick a drug that works and is safe to give while pregnant.

Run through the list. Retinoids cause severe birth defects and are forbidden in pregnancy. Methotrexate is teratogenic and can cause miscarriage, so it is out. PUVA needs psoralen, which is not recommended in pregnancy. That leaves systemic corticosteroids, which are the accepted first line for impetigo herpetiformis and are reasonably safe for the fetus.

So the only choice that balances disease control with fetal safety is corticosteroids.
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