Question:easy
TRALI occurs within how many hours of transfusion?
TRALI occurs within how many hours of transfusion?
Show Hint
TRALI is acute - onset is during or within 6 hours of the transfusion.
Updated On: Jun 23, 2026
- 48 Hrs
- 72 Hrs
- 6 Hrs
- 12 Hrs
Show Solution
The Correct Option is C
Solution and Explanation
Step 1: Treat this as a definition question. TRALI is defined by the timing of the lung injury relative to the transfusion, so the answer is fixed by the standard diagnostic criteria.
Step 2: The accepted window is onset during or within $6$ hours of transfusion. Beyond that window, an alternative diagnosis (such as TACO or delayed reactions) is favoured. Hence the correct figure is $6$ hours.
Step 3: What you would see: sudden non-cardiogenic pulmonary oedema with hypoxaemia, fever, and hypotension, and a chest film showing bilateral fluffy infiltrates resembling ARDS but without raised filling pressures.
Step 4: The longer options of $12$, $48$ and $72$ hours fall outside the acute window and are therefore incorrect.
So TRALI occurs within 6 hours of transfusion.\[\boxed{6\ \text{hours}}\]
Step 2: The accepted window is onset during or within $6$ hours of transfusion. Beyond that window, an alternative diagnosis (such as TACO or delayed reactions) is favoured. Hence the correct figure is $6$ hours.
Step 3: What you would see: sudden non-cardiogenic pulmonary oedema with hypoxaemia, fever, and hypotension, and a chest film showing bilateral fluffy infiltrates resembling ARDS but without raised filling pressures.
Step 4: The longer options of $12$, $48$ and $72$ hours fall outside the acute window and are therefore incorrect.
So TRALI occurs within 6 hours of transfusion.\[\boxed{6\ \text{hours}}\]
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