Question:medium
The toxic substance released with the rupturing of RBCs during malaria fever is:
The toxic substance released with the rupturing of RBCs during malaria fever is:
Updated On: Jan 16, 2026
- Haematoxyline
- Haematin
- Haemozoin
- Haemin
Show Solution
The Correct Option is C
Solution and Explanation
The Plasmodium parasite, transmitted via infected Anopheles mosquito bites, causes malaria. The parasite's lifecycle involves invading and multiplying within red blood cells (RBCs), ultimately leading to their rupture.
The rupture of RBCs releases various substances, with Haemozoin being the principal toxic component. Haemozoin is a crystalline pigment generated by the Plasmodium parasite as it metabolizes hemoglobin within RBCs. This insoluble substance deposits in tissues, contributing to malaria's symptoms and pathology.
Consequently, Haemozoin is identified as the toxic substance liberated during RBC rupture in malaria.
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