Question:medium
The most common cause of death in systemic lupus erythematosus (SLE) in children is:
The most common cause of death in systemic lupus erythematosus (SLE) in children is:
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The organ most heavily and early involved in childhood lupus drives mortality.
Updated On: Jun 23, 2026
- Lupus nephritis
- Lupus cerebritis
- Libman-Sacks endocarditis
- Anemia and infections
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The Correct Option is A
Solution and Explanation
Eliminate the distractors first. Libman-Sacks endocarditis is a classic lupus finding but is usually clinically silent and rarely the cause of death. Lupus cerebritis is serious but far less common than renal disease. Anemia and infections do contribute to mortality, yet they are downstream and combined, not the single leading cause. That leaves lupus nephritis, which is both the most frequent severe organ involvement in children and the chief driver of death through progressive renal failure. Pediatric lupus runs a more aggressive renal course than the adult form, reinforcing why nephritis tops the mortality list. Best answer: lupus nephritis.
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