Question:medium

The hypoglycaemic effect of Gymnema sylvestre is primarily due to its ability to

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Gymnema sylvestre is known as “sugar destroyer” because it suppresses sweet taste and supports antidiabetic action.
  • Stimulate insulin degradation
  • Regenerate pancreatic \(\beta\)-cells and suppress sweet taste
  • Inhibit glucose absorption only
  • Increase glucagon secretion
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The Correct Option is B

Solution and Explanation

Step 1: Understanding the Concept:
\textit{Gymnema sylvestre} (Gurmar) is a traditional Ayurvedic herb used for managing diabetes. Its name "Gurmar" literally means "sugar destroyer."
Step 2: Detailed Explanation:
1. Gymnemic Acids: The active constituents are a group of triterpenoid saponins called gymnemic acids.
2. Suppression of Taste: When the leaves are chewed, they temporarily paralyze the sweet taste receptors on the tongue, making sugar taste like sand.
3. Pancreatic Effect: Studies suggest that Gymnema extract can increase the regeneration/repair of pancreatic \(\beta\)-cells and stimulate insulin secretion, thus lowering blood glucose levels.
Step 3: Final Answer:
Gymnema is unique in its dual action: reducing the craving for sugar by blocking taste and physically improving the insulin-producing capacity of the pancreas.
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