Question:medium

The equation \[ \log \left( \frac{P_1}{P_2} \right) = \frac{2.303 \cdot \Delta H_v \cdot (T_2 - T_1)}{R \cdot T_1 \cdot T_2} \] is related to:

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The Clausius-Clapeyron equation is crucial for determining enthalpy of vaporization and is used in evaluating drug stability and storage conditions.
Updated On: Jul 14, 2026
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The Correct Option is D

Solution and Explanation

Step 1: Understanding the Question:
The question gives an equation connecting vapor pressures \(P_1\), \(P_2\) at temperatures \(T_1\), \(T_2\), through the enthalpy of vaporization \(\Delta H_v\), and asks which named law this is.

Step 2: Key Formula or Approach:
The Clausius-Clapeyron equation describes how the vapor pressure of a pure substance changes with temperature during a liquid to vapor phase change. Its differential form is
\[ \frac{dP}{dT} = \frac{\Delta H_v}{T \, \Delta V} \]
which, after using the ideal gas approximation for the vapor and integrating between two temperatures, gives the logarithmic (two-point) form.

Step 3: Detailed Explanation:
Integrating between \(T_1\) and \(T_2\), assuming \(\Delta H_v\) stays roughly constant over that range, gives
\[ \ln\left(\frac{P_2}{P_1}\right) = -\frac{\Delta H_v}{R}\left(\frac{1}{T_2}-\frac{1}{T_1}\right) \]
Rearranging and converting to base-10 log using the factor \(2.303\) gives exactly the form in the question,
\[ \log\left(\frac{P_1}{P_2}\right) = \frac{2.303 \, \Delta H_v (T_2 - T_1)}{R \, T_1 T_2} \]
This equation is used in physical pharmacy to find the heat of vaporization of a solvent or drug from vapor pressure readings taken at two known temperatures.

Step 4: Final Answer:
This equation is the Clausius-Clapeyron equation.
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