Step 1: Note the two points. The points are $(1,2)$ and $(4,6)$. We want the straight line distance between them.
Step 2: Recall the distance formula. For points $(x_1,y_1)$ and $(x_2,y_2)$, the distance is \[ d=\sqrt{(x_2-x_1)^2+(y_2-y_1)^2}. \] This comes from the Pythagorean theorem.
Step 3: Find the change in $x$. The horizontal change is $x_2-x_1=4-1=3$.
Step 4: Find the change in $y$. The vertical change is $y_2-y_1=6-2=4$.
Step 5: Square and add. \[ d=\sqrt{3^2+4^2}=\sqrt{9+16}=\sqrt{25}. \]
Step 6: Take the root. The square root of $25$ is $5$. This is the classic $3$-$4$-$5$ right triangle. \[ \boxed{5} \]