Question:medium
The development of chondrosarcoma is related with?
The development of chondrosarcoma is related with?
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Multiple enchondromas with haemangiomas carry a high malignant change risk; Felty is an RA triad.
Updated On: Jun 24, 2026
- Maffucci syndrome
- Felty syndrome
- Both a and b
- None of the above
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The Correct Option is A
Solution and Explanation
Step 1: A chondrosarcoma that grows out of an earlier benign cartilage tumour is termed secondary, and the usual seedbeds are enchondromas and osteochondromas.
Step 2: When enchondromas are multiple, as in Ollier disease, and especially when paired with vascular malformations, as in Maffucci syndrome, the chance of one of them turning cancerous climbs to around a quarter to a third of patients.
Step 3: This dwarfs the risk from a single osteochondroma (about 2%), underlining why Maffucci syndrome is the classic answer for chondrosarcoma association.
Step 4: Felty syndrome is a haematological and rheumatological entity, namely rheumatoid arthritis with a big spleen and low neutrophil count, and carries no cartilage-tumour link, so it is excluded.
\[\boxed{\text{Maffucci syndrome}}\]
Step 2: When enchondromas are multiple, as in Ollier disease, and especially when paired with vascular malformations, as in Maffucci syndrome, the chance of one of them turning cancerous climbs to around a quarter to a third of patients.
Step 3: This dwarfs the risk from a single osteochondroma (about 2%), underlining why Maffucci syndrome is the classic answer for chondrosarcoma association.
Step 4: Felty syndrome is a haematological and rheumatological entity, namely rheumatoid arthritis with a big spleen and low neutrophil count, and carries no cartilage-tumour link, so it is excluded.
\[\boxed{\text{Maffucci syndrome}}\]
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