Step 1: Read the directions by comparing with the standard form:
Divide $2x = 3y = -z$ by 6: $\frac{x}{3} = \frac{y}{2} = \frac{z}{-6}$. Direction $(3, 2, -6)$.
Divide $6x = -y = -4z$ by 12: $\frac{x}{2} = \frac{y}{-12} = \frac{z}{-3}$. Direction $(2, -12, -3)$.
Step 2: Dot product:
$3\cdot2 + 2\cdot(-12) + (-6)(-3) = 6 - 24 + 18 = 0$.
Step 3: Conclusion:
A zero dot product means the lines are at right angles. The "acute angle" asked for is then $\frac\pi2$ itself.
Final Answer:
Option (D).
\[ \boxed{\frac{\pi}{2} \text{ (D)}} \]