Sign to disease: Steeple sign equals croup, that is acute laryngotracheobronchitis.
On a front-on neck X-ray the air column in the subglottis normally has shoulders; in croup the mucosa swells and the air column tapers smoothly to a point, exactly like the spire of a church steeple (also called the wine-bottle or pencil-tip sign). Croup is usually viral, hits toddlers under 2, comes on gradually, and produces biphasic stridor, hoarseness, and a barking cough.
Contrast trick: Do not confuse it with the thumbprint sign of acute epiglottitis, which is a swollen epiglottis on a lateral film and is a more sudden, toxic, drooling illness. Laryngeal papillomatosis would show nodular soft-tissue shadows, and bilateral abductor paralysis is diagnosed by laryngoscopy, neither giving a steeple.
Ref: Bailey and Love, 27th edition.