Question

Some of the exceptional properties of regulatory/allosteric enzymes are:
(A) Their Kinetics do not obey the Michaelis-Menten equation.
(B) They are mostly monomeric in nature.
(C) They have more than one substrate binding sites and the substrate binding to different sites is mutually independent, exclusive and noncooperative.
(D) Binding of effector molecules to them may lead to their activation or inhibition.

• A. (A), (B) and (D) only.
• B. (A), (C) and (D) only.
• C. (A), (B), (C) and (D).
• D. (A) and (D) only.

Hint:

Allosteric enzymes are always multimeric proteins showing cooperative binding (which gives them sigmoidal curves instead of hyperbolic Michaelis-Menten curves). They are regulated via conformation shifts by activators and inhibitors.

Answer 1

The Correct Option is D