Question:medium
Secretory diarrhea is NOT seen in which of the following conditions?
Secretory diarrhea is NOT seen in which of the following conditions?
Show Hint
Think which one causes a fat-laden malabsorptive stool rather than active fluid secretion.
Updated On: Jun 24, 2026
- Phenolphthalein
- Celiac disease
- Cholera
- Addison's disease
Show Solution
The Correct Option is B
Solution and Explanation
Step 1: Approach this by classifying diarrhea mechanistically. The two big groups here are secretory (active electrolyte and water pumping into the lumen, watery, continues even when the patient does not eat) versus malabsorptive or steatorrheal (undigested or unabsorbed nutrients drag water osmotically, fat appears in stool).
Step 2: Sort each option. Cholera is the textbook toxin-mediated secretory state. Phenolphthalein, a stimulant laxative, forces intestinal secretion. Addison's disease falls under endocrine and electrolyte-driven secretory causes. All three belong to the secretory column.
Step 3: Celiac disease sits in the opposite column. Gluten-triggered injury flattens the villi, fat is no longer absorbed, and the patient passes bulky, greasy, foul stools, which is steatorrhea driven by maldigestion and mucosal malabsorption, not by active secretion.
Step 4: The question asks where secretory diarrhea is absent, so the celiac entry is the answer because its mechanism is malabsorptive rather than secretory.
\[\boxed{\text{Celiac disease - secretory diarrhea is NOT seen}}\]
Step 2: Sort each option. Cholera is the textbook toxin-mediated secretory state. Phenolphthalein, a stimulant laxative, forces intestinal secretion. Addison's disease falls under endocrine and electrolyte-driven secretory causes. All three belong to the secretory column.
Step 3: Celiac disease sits in the opposite column. Gluten-triggered injury flattens the villi, fat is no longer absorbed, and the patient passes bulky, greasy, foul stools, which is steatorrhea driven by maldigestion and mucosal malabsorption, not by active secretion.
Step 4: The question asks where secretory diarrhea is absent, so the celiac entry is the answer because its mechanism is malabsorptive rather than secretory.
\[\boxed{\text{Celiac disease - secretory diarrhea is NOT seen}}\]
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