Question:easy

Roth spots are seen in:

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White-centred retinal hemorrhages classically tied to a blood malignancy.
Updated On: Jun 24, 2026
  • Uveal melanoma
  • Acute leukaemia
  • Both a & b
  • None of the above
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The Correct Option is B

Solution and Explanation

Step 1: A Roth spot is identified as a retinal bleed with a distinctive white or pale core, named after Moritz Roth.
Step 2: That central whiteness represents fibrin and platelet clot, focal ischaemia, inflammatory or infectious material, or, in malignancy, collections of tumour cells.
Step 3: The classic systemic associations are leukaemia and infective (subacute bacterial) endocarditis, along with diabetes, severe anaemia, hypertension and other ischaemic states.
Step 4: Uveal melanoma is not a cause of Roth spots, so between the two listed entities the correct one is acute leukaemia.
\[\boxed{\text{Acute leukaemia}}\]
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