Question:medium
Right isomerism is associated with?
Right isomerism is associated with?
Show Hint
The spleen is a left-sided organ, so bilateral right-sidedness means it is missing.
Updated On: Jun 24, 2026
- Asplenia
- Two spleens
- One spleen
- Polysplenia
Show Solution
The Correct Option is A
Solution and Explanation
Approach this by recalling which body half normally carries the spleen and what happens when laterality is duplicated. Heterotaxy syndromes arise when the embryo fails to establish a proper left-right axis, so paired organs become symmetrical instead of asymmetrical. Right isomerism means both halves adopt the morphology of the normal right side; the lungs become bilaterally trilobed and the bronchi bilaterally eparterial. Crucially, the spleen is an organ of the left side, so when the left-sided pattern is replaced by a right-sided pattern on both halves, the spleen simply does not form, giving asplenia. This bilateral right-sidedness, asplenia, and the accompanying complex cyanotic cardiac malformations together constitute Ivemark (asplenia) syndrome. The opposite condition, left isomerism, mirrors a normal left side on both halves and is the one that produces multiple spleens, or polysplenia. Hence two spleens, one spleen, and polysplenia all point toward left isomerism, leaving asplenia as the correct match for right isomerism. \[\boxed{\text{Asplenia}}\]
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