Question:medium
Renal vein thrombosis is associated with all of the following except:
Renal vein thrombosis is associated with all of the following except:
Show Hint
Which option causes papillary necrosis rather than venous thrombosis?
Updated On: Jun 24, 2026
- Trauma
- Sickle cell anemia
- Nephrotic syndrome
- Dehydration
Show Solution
The Correct Option is B
Solution and Explanation
Step 1: Frame the question. The task is to find the condition that is NOT a recognised precipitant of clot formation in the renal vein. Three of the four options are textbook RVT triggers.
Step 2: Confirm the true associations. Trauma can directly injure the vein, dehydration (notably in infants) thickens the blood and promotes stasis, and nephrotic syndrome induces a hypercoagulable state through loss of antithrombin III in the urine. All three are well-established causes.
Step 3: Identify the misfit. Sickle cell anemia damages the kidney mainly through sickling in the vasa recta, leading to papillary necrosis and hematuria rather than thrombosis of the main renal vein. It does not feature in the standard list of RVT causes.
Step 4: Clinical note. Acute RVT in children presents with sudden loss of renal function, while a gradual elderly thrombosis may show only recurrent pulmonary emboli or hypertension; diagnosis is confirmed by selective renal venography. None of this points to sickle cell disease.
Therefore the exception is sickle cell anemia.
\[\boxed{\text{Sickle cell anemia}}\]
Step 2: Confirm the true associations. Trauma can directly injure the vein, dehydration (notably in infants) thickens the blood and promotes stasis, and nephrotic syndrome induces a hypercoagulable state through loss of antithrombin III in the urine. All three are well-established causes.
Step 3: Identify the misfit. Sickle cell anemia damages the kidney mainly through sickling in the vasa recta, leading to papillary necrosis and hematuria rather than thrombosis of the main renal vein. It does not feature in the standard list of RVT causes.
Step 4: Clinical note. Acute RVT in children presents with sudden loss of renal function, while a gradual elderly thrombosis may show only recurrent pulmonary emboli or hypertension; diagnosis is confirmed by selective renal venography. None of this points to sickle cell disease.
Therefore the exception is sickle cell anemia.
\[\boxed{\text{Sickle cell anemia}}\]
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