Step 1: This is a negative stem asking which item does not fit Reye syndrome. Recall that this condition is a fatty liver plus brain swelling that follows a viral infection treated with aspirin in a child.
Step 2: Three of the options are genuine features. Salicylate exposure after influenza or chickenpox is the classic trigger, the fat laden liver becomes enlarged giving hepatomegaly, and disordered hepatic metabolism produces low blood glucose and high ammonia.
Step 3: The biochemical picture is rising transaminases with a normal bilirubin, so the skin and sclera do not turn yellow. Clinically jaundice is not a usual finding, which makes that statement the incorrect one and the correct choice for this question.
\[\boxed{\text{Jaundice}}\]