Question:medium
Regarding neurofibromatosis, all are true except:
Regarding neurofibromatosis, all are true except:
Show Hint
Is neurofibromatosis dominant or recessive?
Updated On: Jun 24, 2026
- Autosomal recessive
- Associated with cataract
- Scoliosis
- Multiple fibroma
Show Solution
The Correct Option is A
Solution and Explanation
Step 1: The stem is a negative question, so the task is to find the single false claim among four. Three options should be established neurofibromatosis features and one should clash with its genetics.
Step 2: Neurofibromatosis is one of the well known autosomal dominant phakomatoses. The classic type one arises from a neurofibromin mutation on chromosome 17 and type two from a mutation on chromosome 22, and an affected parent can pass it on with each pregnancy.
Step 3: Cataract, scoliosis and crops of multiple neurofibromas all genuinely occur in the disease. Only the label autosomal recessive contradicts the dominant inheritance, so that statement is the exception being asked for.
\[\boxed{\text{Autosomal recessive is the false statement}}\]
Step 2: Neurofibromatosis is one of the well known autosomal dominant phakomatoses. The classic type one arises from a neurofibromin mutation on chromosome 17 and type two from a mutation on chromosome 22, and an affected parent can pass it on with each pregnancy.
Step 3: Cataract, scoliosis and crops of multiple neurofibromas all genuinely occur in the disease. Only the label autosomal recessive contradicts the dominant inheritance, so that statement is the exception being asked for.
\[\boxed{\text{Autosomal recessive is the false statement}}\]
Was this answer helpful?
0
