Quinine, a potent antimalarial drug, is obtained from

Question

Identify the structure of the alkaloid having the following characteristics:
(A) It is a coca alkaloid having molecular formula \( \text{C}_9\text{H}_{11}\text{NO} \).
(B) As the free base, it rapidly racemizes.
(C) Its reactions show the presence of a keto group and a tertiary nitrogen atom.
(D) Synthesized by condensing \( \gamma \)-methylaminobutyraldehyde with ethylacetoacetate in buffered solution at pH 7.
Choose the correct answer from the options given below:

Answer 1

Step 1: Understanding the Concept:
Quinine was the first effective treatment for malaria caused by \textit{Plasmodium falciparum}. It is an alkaloid with a long history of use in tropical medicine.
Step 2: Detailed Explanation:
1. Source: Quinine is obtained from the dried bark of trees in the genus Cinchona (Family Rubiaceae).
2. Alkaloids: The bark contains about 6% alkaloids, including Quinine, Quinidine (used for heart rhythm), Cinchonine, and Cinchonidine.
3. Others: \textit{Artemisia} provides Artemisinin. Ergot provides Ergotamine.
Step 3: Final Answer:
Cinchona bark is the definitive natural source of Quinine.

Quinine, a potent antimalarial drug, is obtained from

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The Correct Option is B

Solution and Explanation

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