Question

Patient with recurrent abortion diagnosed to have antiphospholipid syndrome. What will be the treatment?

• A. Aspirin only
• B. Aspirin + Low molecular weight Heparin
• C. Aspirin + Low molecular weight Heparin + Prednisolone
• D. No Treatment

Answer 1

The Correct Option is B

Step 1: Recurrent miscarriage in APS results from antibody-driven clotting at the maternal-placental interface. Effective management must target this hypercoagulable state pharmacologically.
Step 2: The evidence-backed approach pairs an antiplatelet agent (low-dose aspirin) with an anticoagulant (low molecular weight heparin). Together they reduce placental thrombosis and have been shown to raise the live birth rate compared with aspirin used on its own.
Step 3: Because monotherapy with aspirin underperforms, steroids add toxicity rather than benefit, and withholding treatment is unsafe, the dual aspirin-plus-heparin protocol stands as the answer of choice.
\[\boxed{\text{Aspirin + Low molecular weight Heparin}}\]