Question:medium
Oxygen therapy may NOT be useful (and may be harmful) in:
Oxygen therapy may NOT be useful (and may be harmful) in:
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Oxygen worsens oxidative lung injury states.
Updated On: Jun 24, 2026
- Asthma
- Pneumonia
- Subglottic stenosis
- Pulmonary fibrosis
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The Correct Option is D
Solution and Explanation
Step 1: The trick is to spot the condition where extra oxygen aggravates rather than helps lung pathology.
Step 2: High oxygen concentrations generate reactive oxygen species; in oxidative-injury states such as paraquat poisoning, bleomycin lung, and pulmonary fibrosis, this worsens the damage.
Step 3: By contrast, asthma and pneumonia cause hypoxaemia that oxygen directly corrects, and subglottic stenosis benefits from oxygenation while the narrowed airway is managed.
Step 4: Hence, among the options, pulmonary fibrosis is the setting where oxygen therapy may not be useful.
\[\boxed{\text{Pulmonary fibrosis}}\]
Step 2: High oxygen concentrations generate reactive oxygen species; in oxidative-injury states such as paraquat poisoning, bleomycin lung, and pulmonary fibrosis, this worsens the damage.
Step 3: By contrast, asthma and pneumonia cause hypoxaemia that oxygen directly corrects, and subglottic stenosis benefits from oxygenation while the narrowed airway is managed.
Step 4: Hence, among the options, pulmonary fibrosis is the setting where oxygen therapy may not be useful.
\[\boxed{\text{Pulmonary fibrosis}}\]
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