Question:medium
Nikolsky's sign is seen in which of the following conditions?
Nikolsky's sign is seen in which of the following conditions?
Show Hint
Skin slides off with pressure due to loss of epidermal cohesion - seen across many blistering diseases.
Updated On: Jun 24, 2026
- Pemphigus
- Herpes zoster
- Bullous impetigo
- All of the above
Show Solution
The Correct Option is D
Solution and Explanation
Step 1: Define the sign. Nikolsky's sign refers to easy dislodgement of the upper epidermis with gentle sliding pressure, reflecting a weak intra-epidermal or sub-epidermal junction.
Step 2: List positive disorders. The sign appears in pemphigus vulgaris, toxic epidermal necrolysis, Stevens-Johnson syndrome, staphylococcal scalded skin syndrome, bullous impetigo, herpes simplex and varicella-zoster blistering, epidermolysis bullosa and bullous lichen planus.
Step 3: Match to options. Pemphigus, bullous impetigo and herpes zoster are all on this list, so no single choice is exclusive.
Step 4: Therefore the inclusive answer is correct.
\[\boxed{\text{All of the above}}\]
Step 2: List positive disorders. The sign appears in pemphigus vulgaris, toxic epidermal necrolysis, Stevens-Johnson syndrome, staphylococcal scalded skin syndrome, bullous impetigo, herpes simplex and varicella-zoster blistering, epidermolysis bullosa and bullous lichen planus.
Step 3: Match to options. Pemphigus, bullous impetigo and herpes zoster are all on this list, so no single choice is exclusive.
Step 4: Therefore the inclusive answer is correct.
\[\boxed{\text{All of the above}}\]
Was this answer helpful?
0
