Question:medium
Necrotizing lymphadenitis is seen in?
Necrotizing lymphadenitis is seen in?
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One of these conditions is literally named histiocytic necrotizing lymphadenitis.
Updated On: Jun 24, 2026
- Kimura disease
- Kikuchi disease
- Hodgkin disease
- Castleman disease
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The Correct Option is B
Solution and Explanation
Match the descriptive term in the question to the disease that carries it as a formal synonym. Kikuchi disease is literally named histiocytic necrotizing lymphadenitis, so it is the direct answer.
Clinically it is a self-limiting condition of young (often Asian) women presenting with fever and tender cervical nodes. Under the microscope the lymph node shows well-demarcated zones of paracortical necrosis filled with karyorrhectic nuclear debris and crescentic histiocytes, and importantly there are no neutrophils, which helps separate it from infective suppurative nodes and from lupus lymphadenitis.
The distractors each have their own signature pattern: Kimura disease is eosinophil-rich lymphoid hyperplasia, Hodgkin disease is defined by Reed-Sternberg cells, and Castleman disease shows the onion-skin germinal-centre and vascular changes of angiofollicular hyperplasia. None of these is a necrotizing lymphadenitis.
Therefore the answer is Kikuchi disease.
\[\boxed{\text{Kikuchi disease}}\]
Clinically it is a self-limiting condition of young (often Asian) women presenting with fever and tender cervical nodes. Under the microscope the lymph node shows well-demarcated zones of paracortical necrosis filled with karyorrhectic nuclear debris and crescentic histiocytes, and importantly there are no neutrophils, which helps separate it from infective suppurative nodes and from lupus lymphadenitis.
The distractors each have their own signature pattern: Kimura disease is eosinophil-rich lymphoid hyperplasia, Hodgkin disease is defined by Reed-Sternberg cells, and Castleman disease shows the onion-skin germinal-centre and vascular changes of angiofollicular hyperplasia. None of these is a necrotizing lymphadenitis.
Therefore the answer is Kikuchi disease.
\[\boxed{\text{Kikuchi disease}}\]
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